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Go to Admin » Appearance » Widgets » and move Gabfire Widget: Social into that MastheadOverlay zone

What is Hypertrophic cardiomyopathy?

Last weekend on March 18, 2012, Fabrice Muamba, the Bolton football star suffered a cardiac arrest during a FA Cup game in England. Thanks to the early intervention of first responders and the very competent medical staff in and around the field. Today, the news has it that Muamba is talking to doctors and ex-teamate, thus slowly recovering in his London Chest  hospital bed.

We wish him a prompt recovery and we all pray that he returns to the pitch to do what he loved to do: play football.

According to medical doctors, Muamba suffered from Hypertrophic Cardiomyopthy, also known as HCM. What it is exactly? read below:

Hypertrophic Cardiomyopathy. Courtesy ADAM Encyclopedia

Hypertrophic cardiomyopathy (HCM) is a condition in which the heart muscle becomes thick. The thickening makes it harder for blood to leave the heart, forcing the heart to work harder to pump blood.

Causes, incidence, and risk factors

Hypertrophic cardiomyopathy is often asymmetrical, meaning one part of the heart is thicker than the other parts. The condition is usually passed down through families (inherited). It is believed to be a result of several problems (defects) with the genes that control heart muscle growth.

Younger people are likely to have a more severe form of hypertrophic cardiomyopathy. However, the condition is seen in people of all ages.


Chest pain


Fainting, especially during exercise

Heart failure (in some patients)

High blood pressure (hypertension)

Light-headedness, especially with or after activity or exercise

Sensation of feeling the heart beat (palpitations)

Shortness of breath

Other symptoms that may occur are:

Fatigue, reduced activity tolerance

Shortness of breath when lying down

Some patients have no symptoms. They may not even realize they have the condition until it is found during a routine medical exam.

The first symptom of hypertrophic cardiomyopathy among many young patients is sudden collapse and possible death. This is caused by very abnormal heart rhythms (arrhythmias), or from the blockage of blood leaving the heart to the rest of the body.

Hypertrophic cardiomyopathy is a major cause of death in young athletes who seem completely healthy but die during heavy exercise. However, certain normal changes in athletes’ hearts can confuse the diagnosis.

Signs and tests

The health care provider will perform a physical exam and listen to the heart and lungs with a stethoscope. Listening with a stethoscope may reveal abnormal heart sounds or a murmur. These sounds may change with different body positions.

The pulse in your arms and neck will also be checked. The doctor may feel an abnormal heartbeat in the chest.

Tests used to diagnose heart muscle thickness, problems with blood flow, or leaky heart valves (mitral valve regurgitation) may include:

24-hour Holter monitor (heart monitor)

Cardiac catheterization

Chest x-ray


Echocardiography (the most common test) with Doppler ultrasound

MRI of the heart

Transesophageal echocardiogram (TEE)

Not all of these tests are useful for evaluating all of these conditions.

Blood tests may be done to rule out other possible diseases.

If you are diagnosed with hypertrophic cardiomyopathy, your health care provider may recommend that your close blood relatives (family members) be screened for the condition.


The goal of treatment is to control symptoms and prevent complications. Some patients may need to stay in the hospital until the condition is under control (stabilized).

If you have symptoms, you may need medication to help the heart contract and relax correctly. Some medications used include beta-blockers and calcium channel blockers, which may reduce chest pain and other symptoms, particularly with exercise. Medications will often relieve symptoms so patients do not need more invasive treatments.

Some people with arrhythmias may need anti-arrhythmic medications. If the arrhythmia is due to atrial fibrillation, blood thinners may also be used to reduce the risk of blood clots.

Some patients may have a permanent pacemaker placed. However, pacemakers are used less often today than they were in the past.

When blood flow out of the heart is severely blocked, an operation called surgical myectomy may be done. This procedure cuts and removes a portion of the thickened part of the heart. Patients who have this procedure often show significant improvement. If the heart’s mitral valve is leaking, surgery may be done to repair or replace the valve.

In some cases, patients may be given an injection of alcohol into the arteries that feed the thickened part of the heart (alcohol septal ablation), essentially causing a controlled heart attack.

An implantable-cardioverter defibrillator (ICD) may be needed to prevent sudden death. ICDs are used in high-risk patients. High risks include:

Drop in blood pressure during exercise

Family history of cardiac arrest

History of cardiac arrest or ventricular tachycardia

History of unexplained fainting

Life-threatening heart rhythms on a Holter monitor

Severe heart muscle thickness

Expectations (prognosis)

Some people with hypertrophic cardiomyopathy may not have symptoms and live a normal lifespan. Others may get worse gradually or rapidly. The condition may develop into a dilated cardiomyopathy in some patients.

People with hypertrophic cardiomyopathy are at higher risk for sudden death than the normal population. Sudden death can occur at a young age.

Hypertrophic cardiomyopathy is a well-known cause of sudden death in athletes. Almost half of deaths in hypertrophic cardiomyopathy happen during or just after the patient has done some type of physical activity.

If you have hypertrophic cardiomyopathy, always follow your doctor’s advice concerning exercise and medical appointments. Patients are sometimes advised to avoid strenuous exercise.


Dilated cardiomyopathy

Heart failure

Life-threatening heart rhythm problems (arrhythmias)

Severe injury from fainting

Calling your health care provider

Call for an appointment with your health care provider if:

You have any symptoms of hypertrophic cardiomyopathy

You develop chest pain, palpitations, faintness, or other new or unexplained symptoms


If you are diagnosed with hypertrophic cardiomyopathy, your health care provider may recommend that your close blood relatives (family members) be screened for the condition.

Some patients with mild forms of hypertrophic cardiomyopathy are only diagnosed by screening echocardiograms because of their known family history.

If you have high blood pressure, make sure you take your medication and follow your doctor’s recommendations.


Maron BJ. Hypertrophic cardiomyopathy. Zipes DP, Libby P, Bonow RO, Braunwald E, eds.Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. St. Louis, Mo: WB Saunders; 2007:chap 65.
Wexler RK, Elton T, Pleister A, Feldman D. Cardiomyopathy: An overview. Am Fam Physician. 2009;79:778-784.
Bernstein D. Diseases of the myocardium. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 439.

Review Date: 5/17/2010.

Reviewed by: Michael A. Chen, MD, PhD, Assistant Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

to read more, visit the website:

A.D.A.M. Medical Encyclopedia.


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